ELISA Substrates and Reagents
Cell Signaling Technology PathScanR Phospho-c-Kit Tyr719 Sandwich ELISA Kit 50 Kit
PathScanR Phospho-c-Kit Tyr719 Sandwich ELISA Kit 50 Kit
ABclonal Technology Phospho-IP3R-S1756 Rabbit pAb
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Biolegend Purified anti-human CD95 Fas M
Purified anti-human CD95 (Fas) (Maxpar Ready) [DX2]; Isotype: Mouse IgG1, κ; Reactivity: Human, Cynomolgus, Rhesus; Apps: FC, CyTOF; Size: 100 μg
Biolegend APC/Cyanine7 anti-human CD235a
APC/Cyanine7 anti-human CD235a (Glycophorin A) Recombinant [QA19A08] Isotype Mouse IgG2a Reactivity Human Apps FC Size 25 tests
ABclonal Technology Phospho-DDR1-Y792 Rabbit pAb
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
ABclonal Technology Phospho-PEA15-S104 Rabbit pAb
This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.
ABclonal Technology Phospho-NRF2-S40 Rabbit pAb
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
ABclonal Technology Phospho-E-Cadherin-S838/S840 Rabbit pAb
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.
ABclonal Technology ADAM8 Rabbit pAb
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.